Introduction

Living with MS is undoubtedly challenging. Inflammation affects the central nervous system, leading to a range of physical and cognitive symptoms. However, one aspect of MS that often goes unnoticed is its connection to mental health, specifically depression. The interplay between depression and MS can create a complex web of challenges for individuals dealing with both conditions.

Why?

  • Biological factors – The physiological changes in the brain caused by MS can contribute to the development of depression. Lesions and inflammation in the central nervous system may lead to depressive symptoms.

  • Chronic illness burden – The chronic nature of MS, coupled with its unpredictable course, can result in a considerable emotional burden. Individuals may face challenges related to physical limitations, daily activities, and uncertainties about the future, all of which contribute to the development of depression.

  • Impact on quality of life – The symptoms of MS, such as fatigue, pain, and mobility issues, can significantly impact an individual’s quality of life. As these symptoms persist, individuals may experience a decline in their overall well-being, further increasing the risk of depression.

Nutrition and depression in people with MS

Recent research has shed light on the link between diet, inflammation, and mental health in individuals with MS. The Australian-led study followed 190 adults with a clinical diagnosis of demyelination, tracking them over 10 years. Dietary information was collected through a food frequency questionnaire at baseline, five-year, and ten-year follow-ups. Researchers utilised the Dietary Inflammatory Index (DII) and the energy-adjusted DII (E-DII) to assess the inflammatory potential of participants’ diets.

  • Higher dietary inflammatory index scores at baseline and the five-year follow-up were linked to elevated depression and anxiety levels five years later.
  • Worsening depression and anxiety scores were observed between the five- and ten-year follow-up in participants with higher dietary inflammatory index scores.
  • A pro-inflammatory diet exhibited a long-term rather than an immediate effect on depression and anxiety.
  • Interestingly, dietary inflammation scores showed no correlation with fatigue levels, as assessed by the Fatigue Severity Scale.

The findings suggest that adopting an anti-inflammatory diet may be a valuable strategy for managing depression and anxiety in individuals with MS.

Anti-inflammatory diet

Here are some top tips to start with.

  • Prioritise foods rich in antioxidants, omega-3 fatty acids, and phytonutrients. Include fruits, vegetables, whole grains, and fatty fish in your diet.
  • Reduce ultra processed foods high in salt and saturated fats, refined sugar, and fried foods. Limit or eliminate red meat consumption.

Conclusion

As we unravel the intricate relationship between diet, inflammation, and mental health in MS, adopting an anti-inflammatory approach is a promising avenue for enhancing the well-being of individuals living with this complex condition. Integrating these insights into daily life may empower those with MS to proactively manage their mental health and cultivate a positive and resilient mindset in the face of the challenges posed by the condition.

If you would like support on your MS health journey, take a look at the range of nutritional therapy programmes which I offer. Please contact me for a free discovery call for more information. I look forward to working with you soon.